Problem: According to Isaiah, Jesus was “despised and rejected by men.” Yet in the Gospels, even Jesus’ enemies seemed to respect Him, saying as Pilate did, “I find no fault in Him at all” (John 18:38). The Roman soldiers who crucified Jesus exclaimed, “Certainly this was a righteous Man” (Luke 23:47). Indeed, Luke says that Jesus “increased … in favor with God and men” (2:52). Which is true—was Jesus respected or despised?
Solution: Both are true. In general, He was respected by His friends and rejected by His enemies. He was honored by His disciples, but crucified by His foes.
Further, Jesus was more accepted in general in His early ministry, but the antagonism became more intense in His later ministry. So, it depends on who is speaking and when, as to whether Jesus was despised or respected.